TuMorMatch Breast

TuMorMatch: Breast Pathology Panel

Toggle markers ON (+) or OFF (-) to evaluate diagnostic possibilities and molecular subtypes.

🔬 Staining Patterns (Key Markers):
  • GATA3 / TRPS1 / ER / PR / p63: Nuclear
  • Mammaglobin / GCDFP-15: Cytoplasmic
  • Calponin / SMA / SMMHC: Cytoplasmic
  • HER2 / E-cadherin: Membranous
  • p120 Catenin: Membranous (Ductal) / Cytoplasmic (Lobular)
1. Breast Origin
GATA3
OFF
TRPS1
OFF
Mammaglobin
OFF
GCDFP-15
OFF
2. Predictive Markers
ER
OFF
PR
OFF
HER2
OFF
Ki-67 (High >20%)
OFF
3. Invasion (In Situ vs Invasive)
p63 / p40
OFF
Calponin
OFF
Smooth Muscle Actin (SMA)
OFF
SMMHC
OFF
4. Lineage Differentiation (Ductal vs Lobular)
E-cadherin
OFF
p120 (Membranous)
OFF
p120 (Cytoplasmic)
OFF

Diagnostic Possibilities Active Markers: None

Disclaimer: The percentages assigned in the chart are estimated guidelines of diagnostic probability based on clinical weight and epidemiological prevalence within breast IHC panels. TumorMatch is an educational and diagnostic support tool; clinical context remains indispensable, and the final diagnosis is the sole responsibility of the pathologist.